Needle-free bio-microneedling on 99% TOP grade spicules.
Five sets, one activator, one protocol.
CLEAR · FIRM · GLOW · SMOOTH · EVEN
For clinics and aesthetic practitioners · Topical cosmetic, professional use
| What it is | Needle-free bio-microneedling, in four moves | 3 |
| 99% TOP | Why the spicule grade is the whole story | 4 |
| Spec | The raw spicule, as certified | 5 |
| The difference | How BIO-SPICULE differs from other bio-microneedling | 6 |
| Downtime | Low downtime, max effect | 7 |
| Choose a set | Five sets at a glance, with intensity | 8 |
| The five sets | CLEAR · FIRM · GLOW · SMOOTH · EVEN | 9–13 |
| Activator | Step 1B, universal Part B | 14 |
| Kit and protocol | What is in the box, the five clinic steps | 15–16 |
| Aftercare | Client care, and who should wait | 17 |
| For clinics | Wholesale, training, private label | 18 |
| Sources | Where every number comes from | 19 |
Reading the intensity dots. ●○○ gentlest, for first-timers and sensitive skin · ●●○ in between · ●●● stronger resurfacing.
Natural sponge spicules are tiny silica needles, finer than a hair. Massaged into the skin, millions of them open temporary micro-channels in the outer layer, so the actives that follow reach where a cream alone cannot. No needle, no device, no acid peel.
Massage drives the spicules into the outer layer, opening millions of temporary micro-channels.
The actives in the powder and the activator, and the serum that follows, travel through those channels.
The skin reads the micro-channels as a signal to renew.
Spicules shed naturally over 48 to 72 hours, taking dull surface cells with them.
Sponge spicule powder is sold in three commercial grades: 99% TOP, 99% First Class and 70%. BIO-SPICULE V2 uses only the top one.
Why intact matters. Published work on sponge spicules shows that the longer and thinner the spicule, the more it opens the skin. A broken needle is a wasted needle.
Brand names are trademarks of their owners and are named as customers of the spicule source, not as endorsers of BIO-SPICULE.
4| Parameter | Specification |
|---|---|
| Sponge spicule content | not less than 99% |
| Particle size | 95% passing 100 to 180 mesh |
| Broken spicule rate | 5 to 10% (90 to 95% intact) |
| Spicule count | 5 to 6 million per gram (manufacturer, dilution method) |
| Lead | ≤ 10 ppm |
| Arsenic | ≤ 2 ppm |
| Cadmium | ≤ 5 ppm |
| Mercury | ≤ 1 ppm |
| Total plate count | ≤ 1,000 cfu/g |
| Yeast and mould | ≤ 100 cfu/g |
| S. aureus, E. coli, Salmonella | negative |
| Shelf life | three years, sealed |
Finished product: a registered cosmetic skin renewal set, powder made to QB/T 2872 and essence to QB/T 2660, in a certified cosmetic production facility.
5Same spicule raw material as SQT, tuned for comfort. The deep renewal clients ask for, with a prickle for hours and light flaking for 2 to 3 days.
Top grade spicules, 90 to 95% of them intact, so every pass channels evenly.
The spicule powder stays dry until it meets the activator at the chair: 1 to 1, mixed in 15 seconds, straight to the face.
Four forms of hyaluronic acid, two peptides, cica and oat beta-glucan. 0% parabens, 0% phenoxyethanol, zero acid, zero alcohol.
One technique, five sets. Match the set to the skin, and the intensity to the client.
| BIO-SPICULE | Needle microneedling | Chemical peel | |
|---|---|---|---|
| Needles | none, topical paste | yes | none |
| Acid | none in the activator | none | yes |
| Device | none, hands and brush | pen or roller | none |
In laboratory studies on sponge spicules, the micro-channels were numerous, about 850 per square millimetre, and closed only gradually over several days. The skin keeps taking in the actives long after the client has gone home.
No needle, so no open puncture wounds. The channels sit in the outer layer, and the spicules leave on their own as the skin renews.
Sessions are usually spaced 2 to 4 weeks apart, once the skin has fully settled. SMOOTH can be repeated sooner.
| Set | Best for | Intensity |
|---|---|---|
| CLEAR Emerald Green | Acne-prone skin, post-acne marks and pores | ●●● |
| FIRM Sapphire Blue | Refined pores, firmness and barrier support | ●●○ |
| GLOW Rose Pink | Dullness, sallow tone and a rosy glass glow | ●●○ |
| SMOOTH Pearl White | Gentle brightening, fine lines and a smooth glow | ●○○ |
| EVEN Amber Herbal | Stubborn dark patches, spots and uneven tone | ●●● |
Target: acne-prone skin, post-acne marks and pores. For oily, congested skin that wants a clearer, smoother look.
Target: refined pores, firmness and barrier support. For skin losing bounce, with visible pores.
Target: dullness, sallow tone and a rosy glass glow. For tired skin, and before an event.
Target: gentle brightening, fine lines and a smooth glow. Made for first-timers and sensitive skin, and can be repeated sooner than the other sets.
Target: stubborn dark patches, spots and uneven tone. Pair with daily sunscreen between sessions.
Order a box in one set, or mix the five sets freely. A sampler with one pair of every set is the easiest way to match your clients before committing to full boxes.
Cleanse and sanitise with a non-alcoholic antiseptic wipe.
One powder vial plus one activator vial in the bowl. Blend with the brush until smooth, about 15 seconds.
Four quadrants. Firm circles for 7 to 15 minutes, pressure matched to the set and the skin.
Sponge off surface residue with cool distilled water.
Chilled hyaluronic acid or collagen mask, 15 to 20 minutes.
Before you start. Check the list on page 17 for anyone who should wait, and take before photos in the same light and angle you will use at follow up, with the client's consent.
Sunscreen protects the result. Daily sunscreen matters with every set, and most of all with EVEN and GLOW, where the goal is a more even, brighter tone.
ORDER · TRAINING · PRIVATE LABEL
+63 949 702 6016
peptology.ph/bio-microneedling · Mon to Sat, 9am to 6pm PHT
Peptology Labs · Carmona, Cavite, Philippines
| Claim | Source |
|---|---|
| 99% spicule, mesh, broken rate, heavy metals, microbes, shelf life | Raw material certificate of analysis |
| Three grades; 5–6 million per gram; ~75% intact in typical grades; 68x | Spicule manufacturer data |
| Longer, thinner spicules open the skin more | Zhang et al., Pharmaceutics 2021. doi:10.3390/pharmaceutics13122119 |
| Blending breaks and shortens spicules | Tansathien et al., Biol Pharm Bull 2019. doi:10.1248/bpb.b19-00158 |
| ~850 channels per mm², closing over several days | Zhang et al., Biomater Sci 2019 (porcine skin, marine sponge spicules). doi:10.1039/c8bm01555d |
| Freshwater spicules can carry cosmetic actives | Kim et al., J Cosmet Dermatol 2022. doi:10.1111/jocd.14771 |
| Same raw material as SQT | Peptology supply records |
| Protocol, aftercare, activator, kit | PEPTICEUTICAL labels and clinic protocol |
Published studies describe sponge spicules in general, not this product. PEPTICEUTICAL BIO-SPICULE is a topical cosmetic for professional use; it is not a drug or a device and is not intended to diagnose, treat or cure any disease. Results vary by skin type and protocol. Brand names belong to their owners. © 2026 Peptology Labs.
19CLEAR · FIRM · GLOW · SMOOTH · EVEN
Peptology Labs · Carmona, Cavite, Philippines
+63 949 702 6016 · peptology.ph